circEXOC6B interacting with RRAGB, an mTORC1 activator, inhibits the progression of colorectal cancer by antagonizing the HIF1A-RRAGB-mTORC1 positive feedback loop

Abstract Background In recent years, an increasing number of studies have indicated that circular RNA plays crucial roles in regulating tumor development and chemoresistance. Using two high-throughput RNA sequence datasets, we previously found that circEXOC6B was downregulated in colon cancer. Howev...

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ग्रंथसूची विवरण

मुख्य लेखकों:	Xiaomin Li, Jianjun Wang, Weihao Lin, Qinzi Yuan, Yanxia Lu, Haowei Wang, Yujia Chen, Lixia Chen, Peiling Dai, Huaicheng Long, Xuenong Li
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	BMC 2022-06-01
श्रृंखला:	Molecular Cancer
विषय:	Colorectal cancer circEXOC6B hsa_circ_0009043 Circular RNA RRAGB
ऑनलाइन पहुंच:	https://doi.org/10.1186/s12943-022-01600-1
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