Microbial binding module employs sophisticated clustered saccharide patches to selectively adhere to mucins

Abstract The mucus lining wet body surfaces forms the interphase and barrier for the microbiota and resident microbiomes. Large mucin proteins densely decorated with O-glycans make up the mucus lining to entrap, feed and shape the microbiota, and repress biofilm formation and virulence. How mucins e...

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Autors principals:	Thapakorn Jaroentomeechai, Billy Veloz, Cátia O. Soares, Felix Goerdeler, Ana Sofia Grosso, Christian Büll, Rebecca L. Miller, Sanae Furukawa, Irene Ginés-Alcober, Víctor Taleb, Pedro Merino, Mattia Ghirardello, Ismael Compañón, Helena Coelho, Jorge S. Dias, Renaud Vincentelli, Bernard Henrissat, Hiren Joshi, Henrik Clausen, Francisco Corzana, Filipa Marcelo, Ramon Hurtado-Guerrero, Yoshiki Narimatsu
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2025-10-01
Col·lecció:	Nature Communications
Accés en línia:	https://doi.org/10.1038/s41467-025-63756-w
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