Muscle diffusion MRI reveals autophagic buildup in a mouse model for Pompe disease

Abstract Quantitative muscle MRI is increasingly important in the non-invasive evaluation of neuromuscular disorders and their progression. Underlying histopathotological alterations, leading to changes in qMRI parameters are incompletely unraveled. Early microstructural differences of unknown origi...

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Autori principali:	Marlena Rohm, Gabriele Russo, Xavier Helluy, Martijn Froeling, Vincent Umathum, Nicolina Südkamp, Denise Manahan-Vaughan, Robert Rehmann, Johannes Forsting, Frank Jacobsen, Andreas Roos, Yoon Shin, Anne Schänzer, Matthias Vorgerd, Lara Schlaffke
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2023-12-01
Serie:	Scientific Reports
Accesso online:	https://doi.org/10.1038/s41598-023-49971-9
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