Neurotransmitter Mechanisms of Ketamine and Ketamine–Magnesium Sulfate-Induced Hypothermia: Evidence for Serotonergic and Adrenergic Involvement Without GABA_A Contributions

<b>Background:</b> Ketamine and magnesium sulfate are commonly used perioperatively to prevent shivering, a frequent and clinically relevant complication of spinal and general anesthesia. Although their hypothermic effects are well documented, the neurotransmitter mechanisms underlying these effects...

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Principais autores:	Katarina Savić Vujović, Sonja Vučković, Lara Samardžić, Branislava Medić, Dragana Srebro, Ana Jotić, Ivana Ćirković
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2026-02-01
coleção:	Brain Sciences
Assuntos:	ketamine magnesium hypothermia rats serotonergic system noradrenergic system
Acesso em linha:	https://www.mdpi.com/2076-3425/16/2/189
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