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Decoding the human PBMC isonome: isoform-level resolution with single-cell long-read transcriptomics

Long-read single-cell RNA sequencing provides an opportunity to understand human health and disease at a level difficult to resolve with bulk or short-read methods. This approach enables isoform-level investigation of cellular diversity and disease mechanisms and definition of cell-types, rather tha...

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Principais autores: Patricia Hayes Doyle, Madeline L. Page, J. Anthony Brandon, Bernardo Aguzzoli Heberle, Brendan J. White, Ann Marie Stowe, Mark T. W. Ebbert
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2026-05-01
叢編:Frontiers in Genetics
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在線閱讀:https://www.frontiersin.org/articles/10.3389/fgene.2026.1782221/full
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