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Regulatory circuit of human microRNA biogenesis.

miRNAs (microRNAs) are a class of endogenous small RNAs that are thought to negatively regulate protein production. Aberrant expression of many miRNAs is linked to cancer and other diseases. Little is known about the factors that regulate the expression of miRNAs. We have identified numerous regulat...

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Bibliographic Details
Main Authors: Ji Lee, Zhihua Li, Rachel Brower-Sinning, Bino John
Format: Artigo
Language:Inglês
Published: Public Library of Science (PLoS) 2007-04-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC1853126?pdf=render
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