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A Photoelectrochemical Biosensor Mediated by CRISPR/Cas13a for Direct and Specific Detection of MiRNA-21

Direct detection of miRNA is currently limited by the complex amplification and reverse transcription processes of existing methods, leading to low sensitivity and high operational demands. Herein, we developed a CRISPR/Cas13a-mediated photoelectrochemical (PEC) biosensing platform for direct and se...

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Principais autores: Yang Zhang, Pei Miao, Jingyuan Wang, Yan Sun, Jing Zhang, Bin Wang, Mei Yan
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2024-09-01
Serier:Sensors
Fag:
CRISPR/Cas13a
photoelectrochemical biosensor
miRNA-21 detection
nucleic acid signal amplification
direct recognition
Online adgang:https://www.mdpi.com/1424-8220/24/18/6138
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