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Long Non-coding RNAs Associated With Neurodegeneration-Linked Genes Are Reduced in Parkinson’s Disease Patients

Transcriptome analysis has identified a plethora of long non-coding RNAs (lncRNAs) expressed in the human brain and associated with neurological diseases. However, whether lncRNAs expression levels correlate with Parkinson’s disease (PD) pathogenesis remains unknown. Herein, we show that a number of...

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Principais autores: Maximilianos Elkouris, Georgia Kouroupi, Alexios Vourvoukelis, Nikolaos Papagiannakis, Valeria Kaltezioti, Rebecca Matsas, Leonidas Stefanis, Maria Xilouri, Panagiotis K. Politis
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019-02-01
Serier:Frontiers in Cellular Neuroscience
Fag:
long-non coding RNAs
Parkinson’s disease
alpha-synuclein
LRRK2
Substantia Nigra
exosomes
Online adgang:https://www.frontiersin.org/article/10.3389/fncel.2019.00058/full
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