CRISPR/Cas9 screen for genome‐wide interrogation of essential MYC‐bound E‐boxes in cancer cells

The transcription factor MYC is a proto‐oncogene with a well‐documented essential role in the pathogenesis and maintenance of several types of cancer. MYC binds to specific E‐box sequences in the genome to regulate gene expression in a cell‐type‐ and developmental‐stage‐specific manner. To date, a c...

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Autori principali:	Marta Kazimierska, Marta Podralska, Magdalena Żurawek, Tomasz Woźniak, Marta Elżbieta Kasprzyk, Weronika Sura, Wojciech Łosiewski, Iwona Ziółkowska‐Suchanek, Joost Kluiver, Anke van denBerg, Natalia Rozwadowska, Agnieszka Dzikiewicz‐Krawczyk
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Wiley 2023-11-01
Serie:	Molecular Oncology
Soggetti:	CRISPR/Cas9 high‐throughput screen MYC MYC target genes transcription factor
Accesso online:	https://doi.org/10.1002/1878-0261.13493
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