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Screening of SGLT2 inhibitors based on virtual screening and cellular experiments

Abstract This study aims at find hit compounds as SGLT2 inhibitors through the methods of virtual screening, biological experiment, Structural similarity search and molecular docking. Computer-aided drug design techniques were used to build modelling of quantitative construct validity relationships....

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Dan Liu, Lei Yu, Mei Ling Cao, Shuai Wang, Nan Zhou, Yan Rong Ren
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Portfolio 2025-08-01
Cyfres:Scientific Reports
Pynciau:
Mynediad Ar-lein:https://doi.org/10.1038/s41598-025-15232-0
Tagiau: Ychwanegu Tag
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