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Aberrant herpesvirus-induced polyadenylation correlates with cellular messenger RNA destruction.

Regulation of messenger RNA (mRNA) stability plays critical roles in controlling gene expression, ensuring transcript fidelity, and allowing cells to respond to environmental cues. Unregulated enhancement of mRNA turnover could therefore dampen cellular responses to such signals. Indeed, several her...

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Autori principali: Yeon J Lee, Britt A Glaunsinger
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2009-05-01
Serie:PLoS Biology
Accesso online:http://europepmc.org/articles/PMC2680333?pdf=render
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