Design, Synthesis, and Self-Assembly of Amphiphilic 1,4-Dihydropyridines Containing Branched Ester Moieties

Amphiphilic cationic lipids based on the 1,4-dihydropyridine (1,4-DHP) scaffold represent a versatile platform for the development of self-assembling delivery systems. In this work, a series of ten new amphiphilic 1,4-DHP derivatives bearing branched ester substituents at the 3,5-positions and quate...

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Detalhes bibliográficos

Principais autores:	Davis Lacis, Martins Rucins, Nadiia Pikun, Ruslans Muhamadejevs, Karlis Pajuste, Mara Plotniece, Juris Jansons, Anna Zajakina, Arkadij Sobolev, Aiva Plotniece
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2026-03-01
Colecção:	Molecules
Assuntos:	1,4-dihydropyridine amphiphiles branched hydrophobic moieties self-assembling properties nanoparticles Lipophilicity (AlogP)
Acesso em linha:	https://www.mdpi.com/1420-3049/31/7/1161
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