Mouse PRDM9 DNA-binding specificity determines sites of histone H3 lysine 4 trimethylation for initiation of meiotic recombination.

Meiotic recombination generates reciprocal exchanges between homologous chromosomes (also called crossovers, COs) that are essential for proper chromosome segregation during meiosis and are a major source of genome diversity by generating new allele combinations. COs have two striking properties: th...

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Autors principals:	Corinne Grey, Pauline Barthès, Gaëlle Chauveau-Le Friec, Francina Langa, Frédéric Baudat, Bernard de Massy
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2011-10-01
Col·lecció:	PLoS Biology
Accés en línia:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22028627/pdf/?tool=EBI
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