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Analysis of the HNF4A isoform-regulated transcriptome identifies CCL15 as a downstream target in gastric carcinogenesis

Objective: Hepatocyte nuclear factor 4α (HNF4A) has been demonstrated to be an oncogene in gastric cancer (GC). However, the roles of different HNF4A isoforms derived from the 2 different promoters (P1 and P2) and the underlying mechanisms remain obscure. Methods: The expression and prognostic value...

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Autores principales: Zhen Ni, Wenquan Lu, Qi Li, Chuan Han, Ting Yuan, Nina Sun, Yongquan Shi
Formato: Artigo
Lenguaje:Inglês
Publicado: China Anti-Cancer Association 2021-05-01
Colección:Cancer Biology & Medicine
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Acceso en línea:http://www.cancerbiomed.org/index.php/cocr/article/view/1813
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