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Patterns and profiles of drug resistance-conferring mutations in Mycobacterium tuberculosis genotypes isolated from tuberculosis-suspected attendees of spiritual holy water sites in Northwest Ethiopia

PurposeThis study examined the patterns and frequency of genetic changes responsible for resistance to first-line (rifampicin and isoniazid), fluoroquinolones, and second-line injectable drugs in drug-resistant Mycobacterium tuberculosis (MTB) isolated from culture-positive pulmonary tuberculosis (P...

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Principais autores: Melese Abate Reta, Nontuthuko Excellent Maningi, P. Bernard Fourie
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2024-03-01
coleção:Frontiers in Public Health
Assuntos:
drug-resistant TB
rpoB
katG
gyrA
mutations
spoligotypes
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fpubh.2024.1356826/full
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