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Development and characterization of chimeric antigen receptor macrophages for amyloid clearance

Systemic amyloidosis is a protein folding disorder characterized by the extracellular deposition of protein fibrils in tissues and vital organs, leading to dysfunction and mortality. While there are monoclonal antibody-based therapies that promote cell-mediated amyloid clearance in various stages of...

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Bibliografiske detaljer
Principais autores: Manasi Balachandran, James S. Foster, Trevor J. Hancock, Emily B. Martin, Joseph W. Jackson, Nicolas Angell, Jonathan S. Wall
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-03-01
Serier:Frontiers in Immunology
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1783851/full
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