Cartilage tissue engineering using decellularized biomatrix hydrogel containing TGF-β-loaded alginate microspheres in mechanically loaded bioreactor

Abstract Physiochemical tissue inducers and mechanical stimulation are both efficient variables in cartilage tissue fabrication and regeneration. In the presence of biomolecules, decellularized extracellular matrix (ECM) may trigger and enhance stem cell proliferation and differentiation. Here, we i...

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Bibliografische Detailangaben

Hauptverfasser:	Sima Bordbar, Zhen Li, Nasrin Lotfibakhshaiesh, Jafar Ai, Amin Tavassoli, Nima Beheshtizadeh, Letizia Vainieri, Mehdi Khanmohammadi, Forough Azam Sayahpour, Mohamadreza Baghaban Eslaminejad, Mahmoud Azami, Sibylle Grad, Mauro Alini
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2024-05-01
Schriftenreihe:	Scientific Reports
Schlagworte:	Cartilage tissue engineering Decellularized biomatrix hydrogel TGF-β1 Alginate microspheres Mechanical stimuli bioreactor
Online-Zugang:	https://doi.org/10.1038/s41598-024-62474-5
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