Intranasal delivery of iron chelators and management of central nervous system disease

Brain iron dyshomeostasis plays a critical role in the pathology of multiple central nervous system (CNS) disorders, including neurodegenerative and neuropsychiatric diseases. Iron chelators such as deferoxamine (DFO) and deferiprone (DFP) have demonstrated therapeutic potential in mitigating diseas...

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Bibliografski detalji

Glavni autori:	Ruiying Cheng, Jonghan Kim
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2025-12-01
Serija:	Frontiers in Pharmacology
Teme:	iron chelation intranasal delivery neurodegenerative diseases blood-brain barrier brain delivery
Online pristup:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1709259/full
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