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Safety of von Willebrand factor substitution for neuraxial anesthesia in women with persistent von Willebrand deficiency at delivery

Background: Neuraxial anesthesia (NA) constitutes a risk for patients with bleeding disorders, the main hemorrhagic adverse effect being spinal epidural hematoma. No clear recommendation has been issued concerning NA use for delivery in patients with von Willebrand disease (VWD) whose von Willebrand...

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Автори: Yaquine Mechelfekh, Sarah Guérin, Kenza Kali, Pauline Noyel, Aurélie Montmartin, Marie Tuffigo, Maud Colinart-Thomas, Alexandre Butelet, Benoit Guillet, Céline Falaise, Nicolas Drillaud, Miréla Chirila-Hetsch, Alain Ramassamy, Philippe Beurrier, Brigitte Tardy
Формат: Artigo
Мова:Inglês
Опубліковано: Elsevier 2026-05-01
Серія:Research and Practice in Thrombosis and Haemostasis
Предмети:
von Willebrand diseases
von Willebrand factor
delivery, obstetric
anesthesia, obstetrical
patient safety
Онлайн доступ:http://www.sciencedirect.com/science/article/pii/S2475037926034540
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