Targeting estrogen-regulated system xc − promotes ferroptosis and endocrine sensitivity of ER+ breast cancer

Abstract Estrogen receptor positive (ER+) breast cancer accounts for approximately 70% of cases. Endocrine therapies targeting estrogen are the first line therapies for ER+ breast cancer. However, resistance to these therapies occurs in about half of patients, leading to decreased survival rates. In...

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Váldodahkkit:	Jiawei Cao, Tong Zhou, Tao Wu, Rixu Lin, Ju Huang, Dejin Shi, Jiawei Yu, Yinrui Ren, Changrui Qian, Licai He, Guang Wu, Zhixiong Dong, Shaofei Yuan, Haihua Gu
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Nature Publishing Group 2025-01-01
Ráidu:	Cell Death and Disease
Liŋkkat:	https://doi.org/10.1038/s41419-025-07354-0
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