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The negative effect of Akkermansia muciniphila-mediated post-antibiotic reconstitution of the gut microbiota on the development of colitis-associated colorectal cancer in mice

The bidirectional relationship between colorectal cancer (CRC) and the gut microbiome has been well-documented. Here, we investigated the impact of Akkermansia muciniphila-mediated post-antibiotic gut microbial reconstitution on the development of colitis-associated CRC (CAC). The results showed tha...

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Principais autores: Kaicen Wang, Wenrui Wu, Qing Wang, Liya Yang, Xiaoyuan Bian, Xianwan Jiang, Longxian Lv, Ren Yan, Jiafeng Xia, Shengyi Han, Lanjuan Li
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2022-10-01
Serier:Frontiers in Microbiology
Fag:
Akkermansia muciniphila
colitis-associated CRC
microbiome
gut microbial reconstruction
gut barrier
inflammation
Online adgang:https://www.frontiersin.org/articles/10.3389/fmicb.2022.932047/full
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