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Development and validation of a machine learning model for predicting hypersplenism in Wilson disease patients

ObjectiveWilson disease (WD) is a rare autosomal recessive copper metabolism disorder, with hypersplenism as a severe, common complication secondary to disease-related cirrhosis. Currently, there is a lack of precise early prediction tools for this complication. This study aimed to construct a hyper...

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Wedi'i Gadw mewn:
Prif Awduron: Qiaoyu Xuan, Xiuquan Shi, Lei Jin, Daiping Hua, Lanting Sun, Wenming Yang, Han Wang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2026-03-01
Cyfres:Frontiers in Medicine
Pynciau:
hypersplenism
LASSO regression
machine learning
predictive model
SHAP analysis
Wilson disease
Mynediad Ar-lein:https://www.frontiersin.org/articles/10.3389/fmed.2026.1768024/full
Tagiau: Ychwanegu Tag
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