Mycotoxin Zearalenone Attenuates Innate Immune Responses and Suppresses NLRP3 Inflammasome Activation in LPS-Activated Macrophages

Zearalenone (ZEA) is a mycotoxin that has several adverse effects on most mammalian species. However, the effects of ZEA on macrophage-mediated innate immunity during infection have not been examined. In the present study, bacterial lipopolysaccharides (LPS) were used to induce the activation of mac...

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Principais autores:	Po-Yen Lee, Ching-Chih Liu, Shu-Chi Wang, Kai-Yin Chen, Tzu-Chieh Lin, Po-Len Liu, Chien-Chih Chiu, I-Chen Chen, Yu-Hung Lai, Wei-Chung Cheng, Wei-Ju Chung, Hsin-Chih Yeh, Chi-Han Huang, Chia-Cheng Su, Shu-Pin Huang, Chia-Yang Li
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2021-08-01
Serija:	Toxins
Teme:	zearalenone mycotoxin innate immunity NLRP3 inflammasome macrophages
Online dostop:	https://www.mdpi.com/2072-6651/13/9/593
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