Biosensor-integrated transposon mutagenesis reveals rv0158 as a coordinator of redox homeostasis in Mycobacterium tuberculosis

Mycobacterium tuberculosis (Mtb) is evolutionarily equipped to resist exogenous reactive oxygen species (ROS) but shows vulnerability to an increase in endogenous ROS (eROS). Since eROS is an unavoidable consequence of aerobic metabolism, understanding how Mtb manages eROS levels is essential yet ne...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Somnath Shee, Reshma T Veetil, Karthikeyan Mohanraj, Mayashree Das, Nitish Malhotra, Devleena Bandopadhyay, Hussain Beig, Shalini Birua, Shreyas Niphadkar, Sathya Narayanan Nagarajan, Vikrant Kumar Sinha, Chandrani Thakur, Raju S Rajmani, Nagasuma Chandra, Sunil Laxman, Mahavir Singh, Areejit Samal, Aswin N Seshasayee, Amit Singh
Formato:	Artigo
Idioma:	Inglês
Publicado em:	eLife Sciences Publications Ltd 2023-08-01
coleção:	eLife
Assuntos:	Mycobacterium tuberculosis redoxosome endogenous ROS lipid metabolism methylcitrate cycle carbon source
Acesso em linha:	https://elifesciences.org/articles/80218
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!