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The inhibition of adenylate kinase by 2,4-thiazolidinedione evaluated by protein-ligand docking

Due to its crucial role in nucleotide metabolism, adenylate kinase deserves a special attention in screening of potential inhibitors. Herein, we report the assessment of the relative orientation of the ligand 2,4-thiazolidinedione to adenylate kinase crystallized in closed conformation. Protein-liga...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолч: Mihaela Ileana Ionescu
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: International Association of Physical Chemists (IAPC) 2017-03-01
Цуврал:ADMET and DMPK
Нөхцлүүд:
Онлайн хандалт:http://pub.iapchem.org/ojs/index.php/admet/article/view/327
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