C16ORF70/MYTHO promotes healthy aging in C.elegans and prevents cellular senescence in mammals

The identification of genes that confer either extension of life span or accelerate age-related decline was a step forward in understanding the mechanisms of aging and revealed that it is partially controlled by genetics and transcriptional programs. Here, we discovered that the human DNA sequence C...

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Principais autores:	Anais Franco-Romero, Valeria Morbidoni, Giulia Milan, Roberta Sartori, Jesper Wulff, Vanina Romanello, Andrea Armani, Leonardo Salviati, Maria Conte, Stefano Salvioli, Claudio Franceschi, Viviana Buonomo, Casey O. Swoboda, Paolo Grumati, Luca Pannone, Simone Martinelli, Harold B.J. Jefferies, Ivan Dikic, Jennifer van der Laan, Filipe Cabreiro, Douglas P. Millay, Sharon A. Tooze, Eva Trevisson, Marco Sandri
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 2024-08-01
Colecção:	The Journal of Clinical Investigation
Assuntos:	Aging Cell biology
Acesso em linha:	https://doi.org/10.1172/JCI165814
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