Dual roles of influenza B virus neuraminidase mRNA vaccine in enhancing cross-lineage protection by supplementing inactivated split vaccination

ABSTRACT The current influenza vaccine is based on immunity to hemagglutinin (HA) and provides poor cross-protection. Here, we generated mRNA vaccine encoding influenza B virus (IBV) neuraminidase (NA) conjugated to influenza A virus M2 ectodomain (M2e), encapsulated in lipid nanoparticles (LNP), ca...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Chau Thuy Tien Le, Ki-Hye Kim, Jannatul Ruhan Raha, Noopur Bhatnagar, Surya Sekhar Pal, Phillip Grovenstein, Mahmuda Yeasmin, Rong Liu, Bao-Zhong Wang, Sang-Moo Kang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology 2025-05-01
Edice:	Journal of Virology
Témata:	NA mRNA-LNP split IBV vaccines cross-protection influenza virus
On-line přístup:	https://journals.asm.org/doi/10.1128/jvi.02294-24
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!