Kinesin-5-independent mitotic spindle assembly requires the antiparallel microtubule crosslinker Ase1 in fission yeast

Bipolar spindle assembly requires a balance of kinesin 14 pulling and kinesin 5 pushing forces. Here, the authors show that in fission yeast, spindle formation can occur in the absence of kinesin 5 (Cut7) and 14 (Pkl1) but requires the microtubule-associated protein Ase1 for spindle bipolarity.

Библиографические подробности

Главные авторы:	Sergio A. Rincon, Adam Lamson, Robert Blackwell, Viktoriya Syrovatkina, Vincent Fraisier, Anne Paoletti, Meredith D. Betterton, Phong T. Tran
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Nature Portfolio 2017-05-01
Серии:	Nature Communications
Online-ссылка:	https://doi.org/10.1038/ncomms15286
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