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Distinct Roles of m5C RNA Methyltransferase NSUN2 in Major Gynecologic Cancers

RNA methylation has recently emerged as an important category of epigenetic modifications, which plays diverse physiopathological roles in various cancers. Recent studies have confirmed the presence of 5-methylcytosine (m5C) modification on mammalian mRNAs, mainly modified by NOP2/Sun RNA methyltran...

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Principais autores: Lingfang Wang, Jian Zhang, Yingfeng Su, Yasen Maimaitiyiming, Siqi Yang, Zhangjin Shen, Shitong Lin, Shizhen Shen, Guankai Zhan, Fenfen Wang, Chih-Hung Hsu, Xiaodong Cheng
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2022-02-01
Serier:Frontiers in Oncology
Fag:
NSUN2
m5C
cervical cancer
ovarian cancer
endometrial cancer
YBX1
Online adgang:https://www.frontiersin.org/articles/10.3389/fonc.2022.786266/full
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