An integrated multi-omics approach to identify regulatory mechanisms in cancer metastatic processes

Abstract Background Metastatic progress is the primary cause of death in most cancers, yet the regulatory dynamics driving the cellular changes necessary for metastasis remain poorly understood. Multi-omics approaches hold great promise for addressing this challenge; however, current analysis tools...

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Detalhes bibliográficos

Principais autores:	Saba Ghaffari, Casey Hanson, Remington E. Schmidt, Kelly J. Bouchonville, Steven M. Offer, Saurabh Sinha
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2021-01-01
coleção:	Genome Biology
Assuntos:	Colon cancer Metastasis Transcriptional regulation Multi-omics Probabilistic model
Acesso em linha:	https://doi.org/10.1186/s13059-020-02213-x
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