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The relationship between regulatory changes in cis and trans and the evolution of gene expression in humans and chimpanzees

Abstract Background Comparative gene expression studies in apes are fundamentally limited by the challenges associated with sampling across different tissues. Here, we used single-cell RNA sequencing of embryoid bodies to collect transcriptomic data from over 70 cell types in three humans and three...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kenneth A. Barr, Katherine L. Rhodes, Yoav Gilad
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BMC 2023-09-01
Cyfres:Genome Biology
Pynciau:
Mynediad Ar-lein:https://doi.org/10.1186/s13059-023-03019-3
Tagiau: Ychwanegu Tag
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