Development and evaluation of novel zein-based artemisinin sustained-release formulation for treating drug-resistant malaria
ABSTRACT Artemisinin antimalarial drugs initially exhibited remarkable efficacy against Plasmodium falciparum. However, their poor solubility and low bioavailability necessitate high doses and lead to an extremely short in vivo half-life. These limitations not only drive the emergence of drug-resist...
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| Principais autores: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2026-02-01
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| Serier: | mBio |
| Fag: | |
| Online adgang: | https://journals.asm.org/doi/10.1128/mbio.03696-25 |
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