A SUMO-dependent feedback loop senses and controls the biogenesis of nuclear pore subunits

The nuclear pore complex is crucial for mediating nucleocytoplasmic exchanges. Here the authors use budding yeast to reveal a mechanism responsible of maintaining nucleoporin homeostasis by sensing changes in the complex integrity and further altering the metabolism of the corresponding mRNAs.

Dades bibliogràfiques

Autors principals:	Jérôme O. Rouvière, Manuel Bulfoni, Alex Tuck, Bertrand Cosson, Frédéric Devaux, Benoit Palancade
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2018-04-01
Col·lecció:	Nature Communications
Accés en línia:	https://doi.org/10.1038/s41467-018-03673-3
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