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Epigenetic Modifications of MiRNAs in Osteoarthritis: A Systematic Review on Their Methylation Levels and Effects on Chondrocytes, Extracellular Matrix and Joint Inflammation

Osteoarthritis (OA) is a joint disorder characterized by progressive degeneration of cartilage extracellular matrix (ECM), chondrocyte hypertrophy and apoptosis and inflammation. The current treatments mainly concern pain control and reduction of inflammation, but no therapeutic strategy has been id...

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Principais autores: Francesca Veronesi, Viviana Costa, Daniele Bellavia, Valentina Basoli, Gianluca Giavaresi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2023-07-01
coleção:Cells
Assuntos:
Acesso em linha:https://www.mdpi.com/2073-4409/12/14/1821
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