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HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4

Several studies have previously shown that histone deacetylase 4 (HDAC4) can regulate endoplasmic reticulum stress‐induced apoptosis through the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway, thereby affecting the progression of osteoarthr...

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Principais autores: Jingrui Huang, Yukun Xu, Yujia Li, Yiming Pang, Xueting Ding, Raorao Zhou, Dan Liang, Xianda Che, Yuanyu Zhang, Chunfang Wang, Wenjin Li, Pengcui Li
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2025-05-01
Serier:FEBS Open Bio
Fag:
apoptosis
ATF4/CHOP signaling pathway
HDAC4
osteoarthritis
transgenic mouse
Online adgang:https://doi.org/10.1002/2211-5463.13965
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