8-[(4-benzylpiperazin-1-yl)methyl]-3-(2-chlorophenyl)-7-hydroxy-chromen-4-one is an activator of contractile activity of intestinal smooth muscles with reversible M2 cholinomimetic properties

Background. Several pathologies (such as diabetes mellitus, Parkinson’s and Alzheimer’s diseases, multiple sclerosis, etc.) are accompanied by degeneration of cholinergic neurons, which are key regulators of the contractile function of the gastrointestinal tract walls, leading to atony and paresis....

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Autors principals:	Olga Tsymbalyuk, Ivan Voiteshenko, Sergii Starosyla, Volodymyr Bdzhola, Andriy Prykhodko, Tetyana Fedirko, Oleksandr Savchenko, Anna Bakhina, Oleksii Nyporko
Format:	Artigo
Idioma:	Inglês
Publicat:	Львівський національний університет імені Івана Франка 2023-12-01
Col·lecció:	Біологічні студії
Matèries:	smooth muscle of the large intestine muscarinic acetylcholine receptors of the m2 subtype acetylcholine spontaneous contractions mechanokinetic analysis
Accés en línia:	http://publications.lnu.edu.ua/journals/index.php/biology/article/view/3711
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