Increased protein expression of interleukin-10 and its signalling molecules in colon cancer progression: potential prognostic and therapeutic targets

Abstract Background Interleukin-10 (IL-10) regulates immune responses in solid tumours, but its role in colorectal cancer (CRC) is unclear due to inconsistent findings. Tumour location is a critical prognostic factor, with proximal tumours often linked to worse outcomes. However, the relationship be...

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Autors principals:	Akhmed Aslam, Bassem Refaat, Riyad A. Almaimani, Ahmad A. Obaid, Abdulrahman Mujalli, Wesam F. Farrash, Mohamed E. Elzubier, Shakir Idris, Afnan Salaka, Ahmed H. Almalki, Mofareh Y. Alkhaldi, Hassan A. Asiri, Mohammad A. Baqassi, Ali M. Alhanash, Othman M. Hakmi, Faisal Minshawi
Format:	Artigo
Idioma:	Inglês
Publicat:	Springer 2025-04-01
Col·lecció:	Discover Oncology
Matèries:	Interleukin-10 receptor α STAT3 Oncogenesis Biological therapy Cell cycle Apoptosis
Accés en línia:	https://doi.org/10.1007/s12672-025-02452-z
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