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Controlled human malaria infection: overview and potential application in the evaluation of transmission-blocking interventions in malaria-endemic areas

Abstract Controlled human malaria infection (CHMI) involves the intentional infection of healthy individuals with malaria parasites, close observation of the volunteers, and clearance of the parasite at a predetermined endpoint. Depending on the need, CHMI can be initiated by either sporozoites or t...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Enock J. Kessy, Ally I. Olotu
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2025-02-01
Schriftenreihe:Malaria Journal
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Online-Zugang:https://doi.org/10.1186/s12936-025-05277-x
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