Triple modal treatment comprising with proton beam radiation, hyperthermia, and gemcitabine/nab-paclitaxel for locally advanced pancreatic cancer: a phase I/II study protocol (TT-LAP trial)

Abstract Background Locally advanced pancreatic ductal adenocarcinoma (PDAC), accounting for about 30% of PDAC patients, is difficult to cure by radical resection or systemic chemotherapy alone. A multidisciplinary strategy is required and our TT-LAP trial aims to evaluate whether triple-modal treat...

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Detalhes bibliográficos

Principais autores:	Osamu Shimomura, Masato Endo, Hirokazu Makishima, Takeshi Yamada, Shinji Hashimoto, Haruko Numajiri, Yoshihiro Miyazaki, Manami Doi, Kinji Furuya, Kazuhiro Takahashi, Toshikazu Moriwaki, Naoyuki Hasegawa, Yoshiyuki Yamamoto, Yusuke Niisato, Mariko Kobayashi, Masashi Mizumoto, Kei Nakai, Takashi Saito, Sodai Hoshiai, Tsukasa Saida, Bryan J. Mathis, Kensaku Mori, Takahito Nakajima, Kiichiro Tsuchiya, Hideyuki Sakurai, Tatsuya Oda
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2023-07-01
coleção:	BMC Cancer
Assuntos:	Locally advanced pancreatic cancer Clinical trial Multidisciplinary treatment Proton beam therapy Hyperthermia
Acesso em linha:	https://doi.org/10.1186/s12885-023-11110-y
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