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The human lncRNA LINC-PINT inhibits tumor cell invasion through a highly conserved sequence element

Abstract Background It is now obvious that the majority of cellular transcripts do not code for proteins, and a significant subset of them are long non-coding RNAs (lncRNAs). Many lncRNAs show aberrant expression in cancer, and some of them have been linked to cell transformation. However, the under...

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Principais autores: Oskar Marín-Béjar, Aina M. Mas, Jovanna González, Dannys Martinez, Alejandro Athie, Xabier Morales, Mikel Galduroz, Ivan Raimondi, Elena Grossi, Shuling Guo, Ana Rouzaut, Igor Ulitsky, Maite Huarte
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2017-10-01
Serier:Genome Biology
Fag:
LncRNA
Cancer
Cell invasion
Epigenetic regulation
PRC2
Online adgang:http://link.springer.com/article/10.1186/s13059-017-1331-y
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