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RIG-I drives protective type I interferon production by glial cells in response to Neisseria meningitidis and Streptococcus pneumoniae challenge

IntroductionBacterial meningitis is a rapidly progressing and often fatal infection of the central nervous system (CNS), characterized by glial cell activation and potent neuroinflammatory responses. While Toll-like receptors have been well-characterized in CNS immunity, the contribution of cytosoli...

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Autors principals: Krishna J. Majithia, M. Brittany Johnson
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2025-11-01
Col·lecció:Frontiers in Immunology
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1692421/full
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