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Pharmacogenomics of intravenous immunoglobulin response in Kawasaki disease

IntroductionKawasaki disease (KD) is a diffuse vasculitis in children. Response to high dose intravenous gamma globulin (IVIG), the primary treatment, varies according to genetic background. We sought to identify genetic loci, which associate with treatment response using whole genome sequencing (WG...

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Príomhchruthaitheoirí: Sadeep Shrestha, Howard W. Wiener, Hidemi Kajimoto, Vinodh Srinivasasainagendra, Dolena Ledee, Sabrina Chowdhury, Jinhong Cui, Jake Y. Chen, Mikayla A Beckley, Luz A. Padilla, Nagib Dahdah, Hemant K. Tiwari, Michael A. Portman
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Frontiers Media S.A. 2024-01-01
Sraith:Frontiers in Immunology
Ábhair:
Kawasaki disease
whole genome sequencing
IVIG refractory
ancestry
Pharmacaeconomics
Rochtain ar líne:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1287094/full
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