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Identification and enrichment of potential pathways in the buffy coat of patients with DRE using non-targeted metabolomics integrated with GEO Datasets

Abstract Background This study aims to identify potential biomarkers in the buffy coat of drug-resistant epilepsy (DRE) patients with mesial temporal lobe epilepsy and to elucidate associated pathways. Methods A comprehensive non-targeted metabolomic and Gene Expression Omnibus (GEO) datasets analys...

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Principais autores: Hailin Zhu, Suyue Zheng, Liyuan Xie, Yi Yun, Patrick Kwan, Ben Rollo, Hui Huang
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-04-01
Serier:European Journal of Medical Research
Fag:
Non-targeted metabolomics
Pathways
Bioinformatics
Drug resistant epilepsy
Online adgang:https://doi.org/10.1186/s40001-025-02609-0
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