New-generation taxoid SB-T-1214 inhibits stem cell-related gene expression in 3D cancer spheroids induced by purified colon tumor-initiating cells

<p>Abstract</p> <p>Background</p> <p>Growing evidence suggests that the majority of tumors are organized hierarchically, comprising a population of tumor-initiating, or cancer stem cells (CSCs) responsible for tumor development, maintenance and resistance to drugs. Previously we have shown that the...

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Hlavní autoři:	Rowehl Rebecca A, Savitt Anne G, Zhu Shu, Wang Hichao, Wang Yuan, Das Manisha, Zuniga Edison S, Botchkina Galina I, Leyfman Yan, Ju Jingfang, Shroyer Kenneth, Ojima Iwao
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2010-07-01
Edice:	Molecular Cancer
On-line přístup:	http://www.molecular-cancer.com/content/9/1/192
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