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Genome-scale spatial mapping of the Hodgkin lymphoma microenvironment identifies tumor cell survival factors

Abstract A central challenge in cancer research is to identify the secreted factors that sustain tumor cell survival. This is best exemplified in Hodgkin lymphoma, where malignant cells constitute a minor fraction of the tumor and rely on signals from the microenvironment for survival. Using genome-...

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Bibliografische gegevens
Hoofdauteurs: Vignesh Shanmugam, Neriman Tokcan, Daniel Chafamo, Sean Sullivan, Mehdi Borji, Haley Martin, Gail Newton, Naeem Nadaf, Saoirse Hanbury, Irving Barrera, Dylan Cable, Jackson Weir, Orr Ashenberg, Geraldine Pinkus, Scott Rodig, Caroline Uhler, Evan Macosko, Margaret Shipp, Abner Louissaint, Fei Chen, Todd R. Golub
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Portfolio 2025-12-01
Reeks:Nature Communications
Online toegang:https://doi.org/10.1038/s41467-025-67539-1
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