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Ex Vivo Hypothermic Perfusion Enables 48‐Hour Heart Preservation and Bench‐Top Functional Recovery via Normothermic Reperfusion in a Porcine Model

Background Ex vivo oxygenated perfusion systems are a promising approach to extend cardiac allograft preservation beyond the typical 4 to 6 hours limit allowed by static cold storage (SCS). Hypothermic oxygenated perfusion (HOPE) has been proven to safely preserve donor hearts, yet its underlying mo...

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Principais autores: Chiara Camillo, Morgan K. Moroi, Yaagnik Kosuri, Anthony Campbell, Arianna Adamo, Krushang Patel, Cary Karcher, Sebastian J. Bauer, Diana Albino, Emre Bektik, Ting Peng, Liming Pei, Christine Chan, Kenmond Fung, Miroslav Sekulic, Renu Nandakumar, Erfan Faridmoayer, Claire Kho, Bianca Bernante, Alexander Romanov, Melissa Tamimi, Juan B Grau, Koji Takeda, Giovanni Ferrari
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2026-04-01
coleção:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Assuntos:
cardiac preservation
ex vivo
heart transplant
hypothermic perfusion
Acesso em linha:https://www.ahajournals.org/doi/10.1161/JAHA.125.045800
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