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Anti-MOG IgG in EAE models clinical aspects of pediatric MOGAD

IntroductionMyelin oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD) is a severe, autoantibody-mediated neuroinflammatory syndrome that disproportionately impacts children. Detection of conformation-specific anti-MOG IgG1 in the serum is central to MOGAD diagnosis, yet the patho...

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Autori principali: Yike Jiang, Estefany Y. Reyes, Elliot YH. Lin, Emily C. Troutman, Miranda Lumbreras, Devon T. DiPalma, Heather Van Mater, Mari L. Shinohara
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2026-06-01
Serie:Frontiers in Immunology
Soggetti:
autoantibody
autoimmune
demyelination
EAE
MOGAD
pediatric
Accesso online:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1860892/full
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