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Prolonged neoadjuvant chemotherapy without radiation versus total neoadjuvant therapy for locally advanced rectal cancer: A propensity score matched study

BackgroundAlthough neoadjvuant chemoradiotherapy (CRT) improves the local control rate of locally advanced rectal cancer (LARC), it fails to significantly improve disease-free survival (DFS) and overall survival (OS). We explored the efficacy of prolonged neoadjuvant chemotherapy (pNCT) without radi...

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Main Authors: Xuan Zhao, Peiyi Han, Luyang Zhang, Junjun Ma, Feng Dong, Lu Zang, Zirui He, Minhua Zheng
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Oncology
Subjects:
chemoradiotherapy
rectal cancer
neoadjuvant chemotherapy
recurrence
propensity score
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.953790/full
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