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Minimal residual disease detection by next-generation sequencing in multiple myeloma: Promise and challenges for response-adapted therapy

Assessment of minimal residual disease (MRD) is becoming a standard diagnostic tool for curable hematological malignancies such as chronic and acute myeloid leukemia. Multiple myeloma (MM) remains an incurable disease, as a major portion of patients even in complete response eventually relapse, sugg...

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Main Authors: Valeria Ferla, Elena Antonini, Tommaso Perini, Francesca Farina, Serena Masottini, Simona Malato, Sarah Marktel, Maria Teresa Lupo Stanghellini, Cristina Tresoldi, Fabio Ciceri, Magda Marcatti
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Oncology
Subjects:
multiple myeloma
next gene sequencing
treatment strategy
complete response
minimal residual disease
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.932852/full
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