WRN Nuclease‐Mediated EcDNA Clearance Enhances Antitumor Therapy in Conjunction with Trehalose Dimycolate/Mesoporous Silica Nanoparticles

Abstract Current research on tumor fibrosis has focused on cancer‐associated fibroblasts, which may exert dual functions of tumor promotion and inhibition. Little attention has been paid to whether tumor cells themselves can undergo fibrotic transformation and whether they can inhibit parenchymal ce...

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Detalhes bibliográficos

Principais autores:	Yinan Li, Xiu Huang, Yingying Li, Qingqing Qiao, Caihong Chen, Yang Chen, Weilong Zhong, Huijuan Liu, Tao Sun
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2024-10-01
coleção:	Advanced Science
Assuntos:	extrachromosomal DNA granuloma scarring trehalose dimycolate tumor fibrosis
Acesso em linha:	https://doi.org/10.1002/advs.202407026
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